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Depression be Gone

SPRAVATO® (esketamine) at

Mercury Mental Health

Available Monday, January 5, 2026

Esketamine is the S-half of ketamine, while ketamine contains both S and R forms. However, they have similar effects. SPRAVATO® is an FDA-approved nasal spray for adults with treatment-resistant depression. Regular ketamine has no FDA approval. SPRAVATO® is often insurance-covered (with prior authorization), while ketamine is almost never covered.

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Who it’s for

  • Adults who didn’t get better (or couldn’t tolerate side effects) after at least two adequate trials of different antidepressants.

  • If you’ve been struggling with treatment-resistant depression, SPRAVATO® (esketamine) may help. It works differently than standard antidepressants and may help some people within hours to days.

  • Eligibility is determined at your intake visit.

How treatment is scheduled

  • Induction: 2×/week for 4 weeks

  • Optimization: 1×/week for 4 weeks

  • Maintenance: weekly or every 2 weeks, individualized
    (For MDSI: 84 mg twice weekly for 4 weeks, then reassess.)

What to expect at a visit

  • Brief check-in and vitals → self-administer SPRAVATO® under supervision → quiet recovery with monitoring (about 2–2.5 hours total).

  • Day-of tips: no solid food for 2 hours before; no liquids for 30 minutes; bring a driver.

Common effects

Dissociation (“spaced-out” feeling), dizziness, sleepiness, nausea, temporary BP increases, headache, bad taste. We monitor and support you onsite.

How to start

  1. Book the intake with Sam Parmenter on our [Book Now] page.

  2. Insurance & PA: We recommend benefit verification and prior authorization before induction. Our standard prior-auth admin fee applies if your plan requires it. Cash-pay is available on request.

  3. If approved and appropriate, we’ll schedule your induction.

       

Questions? hello@mercurymentalhealth.com

For clinicians & referral partners

We accept referrals for SPRAVATO® only—you keep primary medication management.

  • With a signed ROI, we provide regular updates (start, dose/frequency, attendance, brief response/safety notes).

  • We follow REMS requirements and return patients to you for ongoing care once stable.
    Refer/coordinate: hello@mercurymentalhealth.com | Fax (812) 407-2467

Book initial Appointment with Sam Parmenter Now!​

Disclaimer: This page is informational and not medical advice. Final eligibility and scheduling follow clinical evaluation, REMS rules, and payer requirements.

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